Arthritis: COX-2 selective NSAID [such as Celebrex] caused fewer gastrointestinal problems than non-selective NSAID [diclofenac,ibuprofen] (MDLInx)

Arthritis: COX-2 selective NSAID [such as Celebrex] caused fewer gastrointestinal problems than non-selective NSAID [diclofenac,ibuprofen] (MDLInx)

MediNewsDigest: Prolonged used of NSAID has GI risks, but arthritis patients do not have too many choices. This study compares too classes of NSAIDs : COX-2 selective NSAID (such as Celebrex) and non-selective NSAID (diclofenac). The study shows that COX-2 selective NSAID were four times less GI problems than non-selective NSAID. Click …Read the Rest

Fibromyalgia: Resting brain activity associated with spontaneous fibromyalgia pain

Fibromyalgia: Resting brain activity associated with spontaneous fibromyalgia pain

MediNewsDigest: Another study shows FM patients have altered brain activities: This link will bring you to a   Eurekalert abstract.  Quoting Eurekalert: “… Our results clearly show that individuals with FM have greater connectivity between multiple brain networks and the insular cortex, which is a brain region previously linked with evoked pain …Read the Rest

Study:Fructose Promotes Pancreatic Cancer Growth (aacrjournal)

Study:Fructose Promotes Pancreatic Cancer Growth (aacrjournal)

MediNewsDigest: Folks, research shows that fructose can bring some serious health problems. This work published by the American Association for Cancer Research is just one more study showing possible problems with fructose. Note that this article does not specifically target High Fructose Corn Syrup (HFCS).  To get some background about this, see …Read the Rest

Science and myth in dietary supplementation (I)

Science and myth in dietary supplementation (I)

  MediNewsDigest:  The public and the supplement industry are sometimes quick to jump on the bandwagon of  extrapolation of studies showing the benefits of this or that vitamin or mineral or combination thereof.  This is why MediNewsDigest is so interested in clinical nutrition, and other nutrition studies with serious academic credentials. The following …Read the Rest

Multiple Sclerosis: Promising preclinical studies of methylthioadenosine (PubMed)

Multiple Sclerosis: Promising preclinical studies of methylthioadenosine (PubMed)

MediNewsDigest:  Methylthioadenosine (MTA) shows promise as a possible treatment of MS in this reference from PubMed, (entry jul 29,2010) the National Center for Biotechnology Information/ National Institute of Health (NIH).   Quoting:”… the highest dose of MTA (60 mg/kg) was more efficacious than mouse interferon-beta or Glatiramer acetate  [Copaxone,Teva]….Combination therapy assays between MTA and interferon-beta …Read the Rest

Prevalence and Characteristics of Tinnitus among US Adults (sciencedirect)

Prevalence and Characteristics of Tinnitus among US Adults (sciencedirect)

MediNewsDigest: Finally some stats about tinnitus Main conclusions  from this epidemiology type study mentionned in sciencedirect: 1) Non-hispanic white have a high prevalence 2) 14.3% of americans  between 60 and 69 years of age have it 3) Causes from physical (firearms, loud music etc.) to mental ( generalized anxiety disorder) However the …Read the Rest

Effect of brown algae on oxidative stress and inflammation (sciencedirect)

Effect of brown algae on oxidative stress and inflammation (sciencedirect)

MediNewsDigest:  The brown algae component of interest is phloroglucinol, a monomer of phlorotannins. This link to ScienceDirect will bring you to the article. Quoting: “….results suggest that phloroglucinol can provide a therapeutic potential for prevention of chronic inflammation….”   The tone of the paper is very upbeat, we shall see. The conclusion …Read the Rest

Diabetes: Wireless Implanted Tissue Glucose Sensor Tested on Animals (ScienceTranslationalMedicine)

Diabetes: Wireless Implanted Tissue Glucose Sensor Tested on Animals (ScienceTranslationalMedicine)

Quoting the abstract from ScienceTranslationalMedicine,Ref 1 “….The sensor telemetry system functioned continuously while implanted in subcutaneous tissues of two pigs for a total of 222 and 520 days, respectively, with each animal in both nondiabetic and diabetic states….” MediNewsDigest: This is particularly important for cases requiring very frequent  monitoring of …Read the Rest

Anti-cancer effects of broccoli ingredient explained (eurekalert)

Anti-cancer effects of broccoli ingredient explained (eurekalert)

eurekalert: This link  has a more restrictive scope than suggested, prostate cancer only. still worth reading

Targeted Immunotherapy: Metastatic Breast, Pancreatic Cancers (medicalnewstoday)

Targeted Immunotherapy: Metastatic Breast, Pancreatic Cancers (medicalnewstoday)

MediNewsDigest: Quoting MedicalNewsToday: “..The antibody, known as anti-CD25 mAb dacluzimab, targets T regulatory cells (Tregs), naturally occurring cells which tumors harness to dampen the body’s normal immune response….Penn Medicine team’s approach uses the antibody to turn off the Treg cells’ function in the immune system and boosting the effectiveness of …Read the Rest

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