NeuroTalk has an important post on MS wrong diagnosis.[1] The list of diseases that can mascarade as MS is extensive.
- Auto-Immune Diseases
Systemic Lupus Erythematosus (SLE),
Sjögren’s Syndrome,
- Infectious Diseases:
- Vascular:
- Others
Fact is, an MS diagnosis is the result of a combination of MRI lesions readings , neurologist clinical exams, spinal taps .
Keep in mind that the brain lesions seen on MRI are not specific enough by themselves [3,4]
“… MRI evidence plays a supportive role in what is ultimately a clinical diagnosis of MS, in the appropriate clinical situation, and always at the exclusion of alternative diagnoses…”[4]
- NeuroTalk ; “Diseases that can mimic MS”
- NIH ; “Detection of DTI White Matter Abnormalities in Multiple Sclerosis Patients” ; 2008
- Lancet Neurology ; “MRI and the diagnosis of multiple sclerosis: expanding the concept of “no better explanation” ; 2006
- Advanced Neurology ; “The role of MRI in the diagnosis of multiple sclerosis.”; 2006


