“…No significant treatment differences were detected in the primary MRI endpoints.”
That begs the question: What is the efficiency of a low dose treatment? Low dose being usually understood as less than 800 IU/day.
Believe or not, a straight answer is elusive. Studies discussed their ability to raise the blood level of Vitamin D supplements to remedy the low level of serum vitamin D in the blood (25-hydroxy-vitamin D (25(OH)D), but few discussed what this remedy accomplishes in terms of slowing down Multiple Sclerosis..
We found a study that confirms expectations of vitamin d as a T-cell modulator. That could be good for any auto-immune disease, as promised in an article of the British Journal of Pharamcology :
“…Emerging evidence suggests that Vitamin D Receptors plays important roles in modulating cardiovascular, immunological, metabolic and other functions…”
However, the efficacy of Vitamin D was further questioned in a study published in Neurology.org 
“…While the high-dose group did reach higher levels of vitamin D, there were no significant differences between the groups in regard to MRI changes…”
This raises further questions about healing a disease that destroys a nutrient through re-compensating to the nutrient loss.
Note that nobody talks about Vitamin D and progressive MS
Talk to your Doctor
- Neurology ; “”A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis”
- Multiple Sclerosis ; “Vitamin D status and effect of low-dose cholecalciferol and high-dose ergocalciferol supplementation in multiple sclerosis” ; 2009
- Vitamins and Hormones ; “Vitamin D as a T-cell modulator in multiple sclerosis.” ; 2011
- British Journal of Pharmacology ; “Potential for vitamin D receptor agonists in the treatment of cardiovascular disease.” ; 2009
- Neurology.org ; ” Multiple sclerosis and vitamin D” ; Andrew J. Solomon; May 2012