MND: The connection  is still murky. There is circumstantial evidence of the Epstein-Barr Virus (EBV)involvement in MS, as summarized in this study [1]  published in Journal of  Neurology and Neurosurgical Psychiatry.

  • Geographic patterns of occurrence of MS and EBV infection
  • Strong evidence however that people with MS are more likely to report a past history of infectious mononucleosis
  • High levels of Epstein-Barr virus antibodies found in the blood of many MS patients

There is  controversy, because it seems there are conflicting results: Take studies [2] and [3] opposite conclusions: [2] says no EBV in biopsies of MS patients; [3] says EBV found in post-mortem of MS patients…

Your amazing brain.

However, quoting the Center for Disease Control [4]: ” EBV…one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives…”

Clearly, a matter of degree: MS patients seem to have higher EBV presence. Hardly a smoking gun.

There is a nice discussion on the EBV and MS in the Harvard Focus by Jennifer Fraser  [5]. She points out that direct causality proof is not required for the research on EBV to have merit.

However, beware of the human need to pin blame on something. Auto-immune diseases are very complex, as is cancer.

To be continued…

Talk to your Doctor.

Sources:

[1] Journal of Neurology and Neurosurgical Psychiatry; “Epstein–Barr virus and multiple sclerosis”

[2] Brain ; Brigham and Women’s Hospital, Boston ; “Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain.”

[3] Journal of Experimental Medicine ; “Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain”

[4] CDC; “Epstein-Barr Virus and Infectious Mononucleosis

[5] Harvard focus, Jennifer Fraser

 

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