MediNewsDigest:As for many cancers, one turns towards nutrition for prevention or slowing down the beast. In these posts we will summarize the various avenues found in the litterature, and what clinical research says about them.
- We will start with “The role of nutrition in preventing prostate cancer: a review of the proposed mechanism of action of various dietary substances” . This link provides a good start to our topic by providing a list of potential nutritional support against prostate cancer
- carotenoids (e.g., lycopene),
- retinoids (e.g., vitamin A),
- vitamin E,
- vitamin C,
- selenium, polyphenols
- vitamin D
- As a background let us throw in this link to this article :
- “ Oxidative stress in prostate cancer”. This is a very technical article, but the conclusion is clear: “…Thus, many of the factors that are associated with prostate cancer like aging, imbalance of androgens, antioxidant system, dietary fat, and pre malignant conditions like high grade prostate intraepithelial neoplasia etc. may be linked to oxidative stress..”
- Another interesting quote from this rich article is “…Chronic administration of DHT, [Dihydrotestosterone,Wikipedia] and estradiol [wikipedia] to rats induces the expression of inflammation within the prostate..” So, too much male hormone can be a problem in old age, and the female hormone present in the male can be a problem too. Probably not much to do directly with nutrition, but we will see if nutrition can have an indirect effect.
- Let us look at the first item on the list:
- There might be some prostate prevention :”A Prospective Study of Tomato Products, Lycopene, and Prostate Cancer Risk”, JNCI (Journal of the National Cancer Institute]
- But other studies find no benefit: Click here for link to” Prostate Knowledge” from the Harvard Medical School
- So let us see the position of the FDA on this: Quoting the FDA on the effect of Lycopene, if any, on Prostate Cancer:
“Very limited and preliminary scientific research suggests that eating one-half to one cup of tomatoes and/or tomato sauce a week may reduce the risk of prostate cancer. FDA concludes that there is little scientific evidence supporting this claim.”"Qualified Health Claims: Letter Regarding “Tomatoes and Prostate, Ovarian, Gastric and Pancreatic Cancers (American Longevity Petition)” (Docket No. 2004Q-0201)”
- Conclusion: A big maybe for Lycopene benefits against prostate cancer…..