Category Archives: Multiple Sclerosis

IN BRIEF: FDA Just Approved Oral Relapsing Multiple Sclerosis Drug Aubagio

IN BRIEF: FDA Just Approved Oral Relapsing Multiple Sclerosis Drug Aubagio

Teriflunomide (Aubagio, Genzyme/Sanofi) is coming into the MS market [1]. It is an oral drug, nice. Efficacy:  “30% lower than the rate for those taking a placebo,” said Russell Katz, MD,”   What does that mean? Maybe not as clear as just a percent reduction in releases, think compounding. Sagepub …Read the Rest

IN DEPTH: Multiple Sclerosis Research And The Blood Brain Barrier

IN DEPTH: Multiple Sclerosis Research And The Blood Brain Barrier

The Blood Brain Barrier (BBB) is a main focus of Multiple Sclerosis research.  There are currently two main directions for that research: Control of the entry into  the brain of the immune system T-cell crossing through the impaired BBB Sending drugs into the brain directly by overriding the BBB An …Read the Rest

MND BRIEF: Study Shows Multiple Sclerosis Burns Up Vitamin D, But Do Vitamin D supplements fight MS?

MND BRIEF: Study Shows Multiple Sclerosis Burns Up Vitamin D, But Do Vitamin D supplements fight MS?

  A study shows that Multiple Sclerosis (MS) treatment by Interferon-Beta  improves  the ability of the MS patient to produce vitamin D by exposure of their skin to the sun The research was done at the Australian facility  Menzies Research Institute Tasmania Quoting the article [1]: “…In this study, we found …Read the Rest

MND BRIEF: Multiple Sclerosis: Beta interferons (β-IFNs) might not slow disability progression

MND BRIEF: Multiple Sclerosis: Beta interferons (β-IFNs) might not slow disability progression

A new study by the University of British Columbia casts doubt on the benefits of the Interferon treatment against Relapsing-Remitting Multiple Sclerosis Here is the YouTube video from the press release The video tries to mitigate the setback with warm fuzzy statements about future research, but the tone of the …Read the Rest

MND BRIEF:  Multiple Sclerosis And Look Alike Diseases

MND BRIEF: Multiple Sclerosis And Look Alike Diseases

NeuroTalk has an important post on MS wrong  diagnosis.[1]  The list of diseases that can mascarade as MS is extensive. Auto-Immune Diseases Acute Disseminated Encephalomyelitis (ADEM) Systemic Lupus Erythematosus (SLE), Sjögren’s Syndrome, Myasthenia Gravis Infectious Diseases: Lyme disease (LD) Human T-cell lymphotrophic virus-1 (HTLV-1) Vascular: Stroke Central nervous system (CNS) …Read the Rest

MND BRIEF: fMRI Brain Imaging  Enables Severely Motor Disabled To Communicate

MND BRIEF: fMRI Brain Imaging Enables Severely Motor Disabled To Communicate

In addition to not being able to move limb, in severe quadraplegia,  motor-disabled patients can become unable to communicate verbally too, since voice is the result of neuromotorial ability. Those disabled individuals are often fully conscious and awake, making their situation prison like. An amazing development of fMRI technology has crossed …Read the Rest

MS IN BRIEF:  Multiple Sclerosis And Heat Stress Relief

MS IN BRIEF: Multiple Sclerosis And Heat Stress Relief

Multiple sclerosis patients are sensitive to heat. But why? Research on this topic abounds. Quoting the journal of applied physiology [1]: “…The precise mechanisms for impaired neural function in demyelinated axons due to increases in temperature are not completely understood but are likely due to a combination of structural and …Read the Rest

Possible New Treatment of Progressive Multiple Sclerosis: Masitinib

Possible New Treatment of Progressive Multiple Sclerosis: Masitinib

There are few treatments efficacious for the Progressive Forms of Multiple Sclerosis (PPMS and SPMS).  Most of the current treatment consists of anti-inflammatory disease modifying drugs that attempt to re-educate an mistaken immune system. They attack the Relapsing-remitting form of MS Here is a summary of the arsenal: Interferons (all …Read the Rest

MND BRIEF: How Accurate Are The Criteria For The Diagnosis of Chronic Cerebrospinal Venous Insufficiency (CCSVI)?

MND BRIEF: How Accurate Are The Criteria For The Diagnosis of Chronic Cerebrospinal Venous Insufficiency (CCSVI)?

The European Society of neurosonology and cerebral hemodynamics (ESNCH) came out with a strong criticism of  ultrasonographic criteria proposed by the brain hemodynamics community.[1] “…It is also unclear how it was decided that two or more of these five ultrasound criteria may be used to diagnose CCSVI, since no validation of these …Read the Rest

Pain Brief :Study Shows Botulinum Toxin Helpful for the Treatment of Trigeminal Neuralgia

Pain Brief :Study Shows Botulinum Toxin Helpful for the Treatment of Trigeminal Neuralgia

Trigeminal Neuralgia (TN) is a very painful condition. The nerve, which is three pronged as the name implies,  serves the human face, and brings sensory data. The nerve damage can originate  from  compression that can originate from multiple causes, and can also cause demyelination  with progressive  neuro-degeneration (axonal). The term demyelination bring …Read the Rest

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